Miralax And Overstimulation Of Entire Body
Posted 01 February 2010 - 03:18 PM
Won't bore you with too many details. Severe constipation, doctor put me on Miralax every day. The more I take, the more overstimulated I feel. Took it today, almost immediately, bp went up, heartrate went up, felt shaky, feet and hands went cold yet sweaty, instant brain fog, just didn't feel good.
Not an allergic reaction (I have a great deal of experience with those), then within an hour, went to the bathroom. That seems a little soon. I'm not even taking much at all of this stuff, just enough to cover the bottom of the bottle's cap, which is nothing. I'm wondering if anyone else feels overly stimulated by Miralax or any other laxatives. I know my nerves are on edge right now since being in the hospital and having back to back scopes (anesthesia two days in a row), lots of pain meds which I can't do very well, ppi's which get on my nerves (literally), ups and downs with my steroids, etc.
Thanks in advance for sharing your experiences.
Posted 01 February 2010 - 03:58 PM
Posted 01 February 2010 - 05:15 PM
Posted 01 February 2010 - 07:15 PM
Short answer - yes! Anything that gets my bowels moving over-stimulates my whole system and increases all of my symptoms - shaky, cold sweats, tremors, light-headedness, wooziness, headache, etc. I feel the best when I am constipated. With the Miralax - I took it for several years because I had a complete stop of my colon and was laxative dependent. I usually could only handle 1/6 to 1/2 of the suggested 17 gram dose.
Posted 01 February 2010 - 07:42 PM
Hmm, not sure but I'm wondering why he would want to give his car diarrhea? :)
He asked me, "why would I want to take anti freeze".
Posted 02 February 2010 - 09:30 AM
BURDOCK ROOT. That is the best stuff. If I find there's a week gone by and I haven't gone (which hasn't been for a while since I have had my last surgery) I drink two cups of super hot tea, gulp it down real fast. The trick with this is it isn't a laxitive, it makes your intestines secrete goo to loosen the stool, not soften it. So it helps it come out, not turn it into water. So it doesn't take your water out to make you dehydrated. It also comes in pill form for a daily use. It was so gentle...
Posted 02 February 2010 - 10:03 AM
I hate to have misinformation on the board, so I wanted to clarify. Miralax and antifreeze are not the same thing. Miralax is polyethylene glycol (PEG). Antifreeze in monoethylene glycol (MEG). It may not look like much, but there is a big difference. Antifreeze (MEG) is toxic and easily gets into your bloodstream if you drink it. Miralax is nontoxic and less than a half of a percent of Miralax (PEG) enters the blood stream.
I have found some information on the web where children with autism have become ill after taking Miralax. The theory is that these kids have "leaky guts" and too much of the chemical (albeit non-toxic) actually enters the blood stream. There have been other posts about this, but strangely enough autism is being linked to mastocytosis. I know you have MCAD. Thought that connection was weird.
Miralax has been a godsend for me and many others. I was regularly hospitalized with obstructions until taking high (40 grams) daily doses of Miralax. Miralax, along with Milk of Magnesia is considered to be among the safest long-term treatments for folks with severe & chronic constipation. (Many with autonomic dysfunctions suffer with this.)
I don't doubt what is happening to you & hope you are able to find another treatment that works. Sorry you are dealing with this too.
Posted 02 February 2010 - 10:05 AM
Posted 03 February 2010 - 04:36 PM
With PEG, you have to be certain to stay well hydrated or that can really mess you up symptom-wise.
Posted 04 February 2010 - 08:54 AM
Posted 04 February 2010 - 09:51 AM
In the case of PEG, it's base is an "ether", in this case a "poly" ether, meaning multiple ether components:
"Ether is a class of organic compounds that contain an ether group ? an oxygen atom connected to two alkyl or aryl groups ? of general formula R?O?R. A typical example is the solvent and anesthetic diethyl ether, commonly referred to simply as "ether" (CH3-CH2-O-CH2-CH3). Ethers are common in organic chemistry and pervasive in biochemistry, as they are common linkages in carbohydrates and lignin."
...and glycol belongs to the alcohol family of chemicals... and PEG is essentially an indigestible wax; your body cannot process it, so it's essentially passed through undigested. Less than 0.005 is absorbed which is an incredibly small amount. I works as a laxative b/c it tends to absorb water, which basically then adds some fluid to your bowels, helping to move things along. Because of this, your body may lose some fluid, and again, as stated a few times already, it can make you dehydrated if you don't take your normal POTsy precautions of eating enough salty stuff to counter any possible dehydration.
Posted 06 February 2010 - 06:49 PM
I quit taking the Miralax, upped my water intake and began walking again every day (hard to do with all this Ohio snow right now, but went over to the hospital--five minutes away and a public place--and walked the hallways), and I've been okay so far.
I do think my nervous system is very sensitive to stimulants, even small doses of laxative. I know my liver metabolizes really slowly, too, so maybe a build up of Miralax in my system?
Macks Mom, interesting about the leaky gut. I've thought for awhile now that I've probably got that, and maybe that's contributed to all of my food allergies.
I think I'll save the Miralax for only those times I really, really need it.
Thanks, again, everyone, for taking the time to share. I really appreciate it.